May fight other neurological diseases

A decrease in phosphocreatine in your brain is a critical component in various neurological illnesses. Because creatine can raise these levels, it may assist to prevent or halt disease development. Creatine restored the brain's phosphocreatine reserves to 72% of pre-disease levels in mice with Huntington's disease, compared to only 26% in healthy animals. This phosphocreatine replenishment aided in the maintenance of everyday functions and decreased cell death by approximately 25%.

Creatine has also been demonstrated to be beneficial in the treatment of amyotrophic lateral sclerosis (ALS), a disease that damages the motor neurons that are necessary for movement. It enhanced motor function, decreased muscle atrophy, and increased survival by 17%. Although the additional study in humans is needed, some experts believe that creatine supplements, when taken in conjunction with standard medications, can provide protection against neurological illnesses.